162: Congenital cardiac defects and placental vascular malperfusion
نویسندگان
چکیده
منابع مشابه
Congenital Familial Cardiac Conduction Defects.
THE familial occurrence of conduction system disturbances has been reported infrequently in medical literature. Morquio, in 1901,1 reported clinical signs of impaired atrioventricular conduction in five boys in a family of eight children. There was no evidence of consanguinity and the defect did not occur in immediate ancestors nor in collateral branches of the family. In 1903, Sir William Osle...
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Fetoplacental glucocorticoid overexposure is a significant mechanism underlying fetal growth restriction and the programming of adverse health outcomes in the adult. Placental glucocorticoid inactivation by 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) plays a key role. We previously discovered that Hsd11b2(-/-) mice, lacking 11β-HSD2, show marked underdevelopment of the placental vasculat...
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In neonates and infants with congenital heart disease (CHD), cardiovascular magnetic resonance (CMR) is an established imaging modality in all patients in whom echocardiography does not provide sufficient information and definitive diagnosis. CMR is noninvasive, and does not involve vascular catheterization or ionizing radiation. Therefore the use of CMR obviates the potential risks of cardiac ...
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Many patients with congenital cardiac disease are at risk for progressive aortic dilation. The mechanisms underlying aortic dilation in this patient cohort are described, and the similarities to the pathophysiologic alterations seen in Marfan syndrome are highlighted. Indications for treatment are discussed.
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Neonatal patients with congenital cardiac defects require proper diagnosis often by cardiac catheterization before surgical repair. In our institution, patients whose echocardiograms reveal surgically correctable lesions, but who are severely decompensated, have been placed on Extracorporeal Life Support (ECLS) prior to catheterization or surgery. Subsequent management of ECLS and cardiopulmo...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2020
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2019.11.178